ABSTRACT
Objective To assess the consistency of 30 batches of Xueshuan Xinmaining Tablets (XXT), we establish the UPLC-PDA fingerprint of XXT and provide reliable scientific basis for the Chinese medicine quality consistency. Methods Methanol was used to extract the XXT samples, and the extracts were measured by UPLC with the absorption wavelength at 280 nm. Waters Acquity UPLC HSS T3 reversed-phase column (50 mm × 2.1 mm, 1.8 μm) was used for determining the extracts at a flow rate of 0.5 mL/min and column temperature of 40 ℃. The mobile phase condition was acetonitrile-0.1% formic acid aqueous solution with gradient mode. The methodology, similarity calculation and cluster analysis of 30 batches of XXT samples were investigated. The common peak of XXT was belonged to single medicinal materials and common peaks were identified by comparing with the reference. Results The UPLC fingerprint of XXT was established. Twenty-seven common fingerprint peaks were indicated with wavelength 280 nm, Among them, peaks 1, 10, 12-16, 18, and 21-28 belonged to Salviae Miltiorrhizae Radix et Rhizoma (SMRR), peaks 2-4, 6, 8, 9, and 17 belonged to Chuanxiong Rhizoma (CR), peaks 3, 7, 9, 11, and 16 belonged to Ilicis Pubescentis Radix (IPR), peak 5 belonged to Sophora Flos (SF), peaks 19 and 20 belonged to Bufonis Venenum (BV). Peaks 4, 5, 13, 19, 20, and 28 were ferulic acid, rutin, salvianolic acid B,resibufogenin, cinobufagin, tanshinone IIA, respectively, compared with reference. The analyzed samples were classified into two classes and the similarity was greater than 0.960. Conclusion The method of XXT UPLC-PDA fingerprint was established with good precision, stability and repeatability, supplying helpful information for the comprehensive evaluation of XXT.
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Objective To apply barcode technology to the patient information management in the hyperbaric medicine unit to sim plify the workflow of outpatient registration and facilitate access to patient's information.Methods The barcode designed by some hospital and its use were introduced,and then compared with the traditional way on time consuming,patient satisfaction and etc.Results Barcode technology enhanced the nurse's efficiency and the patient's satisfaction.Conclusion Barcode technology simplifies the working flow in the hyperbaric oxygen outpatient,increases medical service quality,decreases medical disputes and meets the requirements for appointment treatment,and thus is worthy promoting practically.
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the diagnostic value of multi-slice spiral CT (MSCT) three dimensional (3D) reconstruction for maxillofacial diseases.</p><p><b>METHODS</b>Sixty patients with maxillofacial diseases underwent the scanning of MSCT with 3D reconstruction. Among them, 34 patients with maxillofacial fracture, 10 patients with maxillofacial tumors and tumor-like diseases, and 16 patients with congenital deformities. The MSCT scanned with slice thickness of 2 mm. The methods of 3D reconstruction included multi-planar reconstruction (MPR), shaded surface display (SSD), and volume rendering (VR). The results were compared with what was observed during operations.</p><p><b>RESULTS</b>Totally 36 cases of maxillofacial fracture were shown by 2D or 3D imaging and were validated by the observations during operation. The MSCT with 3D reconstruction imaging was significantly superior to 2D axial imaging in maxillofacial fracture. Three dimensional imaging could clearly show the spacial anatomy of facial, fragment displacement, and tracing fracture lines. However, 2D imaging had better effectiveness than 3D imaging in observing deep structure and fine fracture. In maxillofacial tumors and tumor-like diseases, 3D imaging was significantly superior to 2D axial imaging in showing the tumor shape and spacial relationships between tumors and surrounding structures. Two dimensional imaging and MPR imaging were excellent to reveal internal structure and pathological changes of tumors. 2D imaging and MPR imaging also achieved better results in showing tumors extended to soft tissues. In maxillofacial congenital deformities, 3D imaging were superior than 2D imaging.</p><p><b>CONCLUSION</b>3D imaging has an important value in the diagnosis and clinical assessment of maxillofacial fracture, tumor-like diseases, and congenital deformities.</p>